Prodrome

From Greek "prodromos" (a running before, a forerunner), combining "pro" (before) with "dromos" (a running, a course). The word entered medical usage to mark the heralding stage of a disease.

  1. noun · /PROH-drohm/

    An early symptom or set of symptoms that signals the onset of a disease before its full features appear.

    The warning phase of an illness — the faint first signs — giving clinicians a term for the window before a condition fully declares itself.

    The tingling on his lip was the familiar prodrome of a cold sore, appearing a day before the blister.

    Distinct from a symptom proper, which marks the established illness; a prodrome is a symptom of what is coming. It differs, too, from a prognosis, which is a forecast of how the disease will unfold, not an early sign of its arrival.